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Short answer: It appears tolerable in very limited early human data, but there is not enough evidence to call it safe for general use

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5B shows much smaller aggregate masses, the majority of which are smaller than 5 um in size

[DOI] [PubMed] [Google Scholar] 39.Heck D.E., Shakarjian M., Kim H.D., Laskin J.D., Vetrano A.M

131 In addition, gene polymorphisms can alter astrocyte responses to pathologies and contribute to disorder progression, as for example with APOE polymorphisms in AD or traumatic injuries, 132,133,134,135 or with CD38 polymorphisms in PD